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Empfehlungsstärke

  • A There is good evidence to support the use of the procedure
  • B There is fair evidence to support the use of the procedure
  • C There is poor evidence to support the use of the procedure
  • D There is fair evidence to support the rejection of the use of the procedure
  • E There is good evidence to support the rejection of the use of the procedure

Evidenz (Qualität der Belege)

  • I Evidence obtained from at least one properly designed, randomized controlled trial
  • II-i Evidence obtained from well-designed controlled trials without randomization
  • II-ii Evidence obtained from well-designed cohort or case–control analytical studies, preferably from more than one centre or research group
  • II-iii Evidence obtained from multiple time series with or without the intervention. Dramatic results in uncontrolled experiments (such as the results of the introduction of penicillin treatment in the 1940s) could also be regarded as this type of evidence
  • III Opinions of respected authorities based on clinical experience, descriptive studies or reports of expert committees
  • IV Evidence inadequate due to problems of methodology (e.g. sample size, or length of comprehensiveness of follow-up or conflicts of evidence).

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